Subretinal Pigment Epithelial Deposition of Drusen Components Including Hydroxyapatite in a Primary Cell Culture Model

PURPOSE: Extracellular deposits containing hydroxyapatite, lipids, proteins, and trace metals that form between the basal lamina of the RPE and the inner collagenous layer of Bruch's membrane are hallmarks of early AMD. We examined whether cultured RPE cells could produce extracellular deposits...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Invest Ophthalmol Vis Sci
Hauptverfasser: Pilgrim, Matthew G., Lengyel, Imre, Lanzirotti, Antonio, Newville, Matt, Fearn, Sarah, Emri, Eszter, Knowles, Jonathan C., Messinger, Jeffrey D., Read, Russell W., Guidry, Clyde, Curcio, Christine A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2017
Schlagworte:
Retinal Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295770/
https://ncbi.nlm.nih.gov/pubmed/28146236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-21060
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge