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Sulfolobus acidocaldarius UDG Can Remove dU from the RNA Backbone: Insight into the Specific Recognition of Uracil Linked with Deoxyribose

Sulfolobus acidocaldarius encodes family 4 and 5 uracil-DNA glycosylase (UDG). Two recombinant S. acidocaldarius UDGs (SacUDG) were prepared and biochemically characterized using oligonucleotides carrying a deaminated base. Both SacUDGs can remove deoxyuracil (dU) base from both double-stranded DNA...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Yi, Gang-Shun, Wang, Wei-Wei, Cao, Wei-Guo, Wang, Feng-Ping, Liu, Xi-Peng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295032/
https://ncbi.nlm.nih.gov/pubmed/28106786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes8010038
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