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In Praise of Descriptive Science: A Breath of Fresh AIRE

Meyer et al. find that subjects lacking the AIRE gene, critical for self-tolerance in T lymphocytes, show a broad range of autoantibody specificities, which can have extremely high affinities. The data also suggest that some of these autoantibodies can, surprisingly, prevent some types of auto-immun...

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Vydáno v:Cell
Hlavní autor: Davis, Mark M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294994/
https://ncbi.nlm.nih.gov/pubmed/27471960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.07.018
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