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A clinically relevant dose of cyclophosphamide chemotherapy impairs memory performance on the delayed spatial alternation task that is sustained over time as mice age

BACKGROUND: Cyclophosphamide chemotherapy is a mainstay of adjuvant breast cancer treatment. Unfortunately, this drug is associated with cognitive impairments in cancer patients that may accelerate cognitive aging. Memory is particularly affected in many patients. In order to better understand the p...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neurotoxicology
Egile Nagusiak: Janelsins, Michelle C, Heckler, Charles E, Thompson, Bryan D, Gross, Robert A, Opanashuk, Lisa A, Cory-Slechta, Deborah A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294923/
https://ncbi.nlm.nih.gov/pubmed/27371410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2016.06.013
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