Induction of complex immune responses and strong protection against retrovirus challenge by adenovirus-based immunization depends on the order of vaccine delivery

BACKGROUND: In the Friend retrovirus mouse model we developed potent adenovirus-based vaccines that were designed to induce either strong Friend virus GagL(85–93)-specific CD8(+) T cell or antibody responses, respectively. To optimize the immunization outcome we evaluated vaccination strategies usin...

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Bibliographic Details
Published in:Retrovirology
Main Authors: Kaulfuß, Meike, Wensing, Ina, Windmann, Sonja, Hrycak, Camilla Patrizia, Bayer, Wibke
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294899/
https://ncbi.nlm.nih.gov/pubmed/28166802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-017-0336-7
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