Dissection of SAP-dependent and SAP-independent SLAM family signaling in NKT cell development and humoral immunity

Signaling lymphocytic activation molecule (SLAM)–associated protein (SAP) mutations in X-linked lymphoproliferative disease (XLP) lead to defective NKT cell development and impaired humoral immunity. Because of the redundancy of SLAM family receptors (SFRs) and the complexity of SAP actions, how SFR...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Chen, Shasha, Cai, Chenxu, Li, Zehua, Liu, Guangao, Wang, Yuande, Blonska, Marzenna, Li, Dan, Du, Juan, Lin, Xin, Yang, Meixiang, Dong, Zhongjun
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294859/
https://ncbi.nlm.nih.gov/pubmed/28049627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161312
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