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The epidermal polarity protein Par3 is a non–cell autonomous suppressor of malignant melanoma

Melanoma, an aggressive skin malignancy with increasing lifetime risk, originates from melanocytes (MCs) that are in close contact with surrounding epidermal keratinocytes (KCs). How the epidermal microenvironment controls melanomagenesis remains poorly understood. In this study, we identify an unex...

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Bibliografiska uppgifter
I publikationen:J Exp Med
Huvudupphovsmän: Mescher, Melina, Jeong, Peter, Knapp, Sina K., Rübsam, Matthias, Saynisch, Michael, Kranen, Marina, Landsberg, Jennifer, Schlaak, Max, Mauch, Cornelia, Tüting, Thomas, Niessen, Carien M., Iden, Sandra
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294851/
https://ncbi.nlm.nih.gov/pubmed/28096290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160596
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