The epidermal polarity protein Par3 is a non–cell autonomous suppressor of malignant melanoma

Melanoma, an aggressive skin malignancy with increasing lifetime risk, originates from melanocytes (MCs) that are in close contact with surrounding epidermal keratinocytes (KCs). How the epidermal microenvironment controls melanomagenesis remains poorly understood. In this study, we identify an unex...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Mescher, Melina, Jeong, Peter, Knapp, Sina K., Rübsam, Matthias, Saynisch, Michael, Kranen, Marina, Landsberg, Jennifer, Schlaak, Max, Mauch, Cornelia, Tüting, Thomas, Niessen, Carien M., Iden, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294851/
https://ncbi.nlm.nih.gov/pubmed/28096290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160596
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