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Trypanosome outer kinetochore proteins suggest conservation of chromosome segregation machinery across eukaryotes

Kinetochores are multiprotein complexes that couple eukaryotic chromosomes to the mitotic spindle to ensure proper segregation. The model for kinetochore assembly is conserved between humans and yeast, and homologues of several components are widely distributed in eukaryotes, but key components are...

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Pubblicato in:J Cell Biol
Autori principali: D’Archivio, Simon, Wickstead, Bill
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294786/
https://ncbi.nlm.nih.gov/pubmed/28034897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201608043
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