Early Effect of Amyloid β-Peptide on Hippocampal and Serum Metabolism in Rats Studied by an Integrated Method of NMR-Based Metabolomics and ANOVA-Simultaneous Component Analysis

Amyloid β (Aβ) deposition has been implicated in the pathogenesis of Alzheimer's disease. However, the early effect of Aβ deposition on metabolism remains unclear. In the present study, thus, we explored the metabolic changes in the hippocampus and serum during first 2 weeks of Aβ (25–35) injec...

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Vydáno v:Biomed Res Int
Hlavní autoři: Du, Yao, Zheng, Hong, Xia, Huanhuan, Zhao, Liangcai, Hu, Wenyi, Bai, Guanghui, Yan, Zhihan, Gao, Hongchang
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294748/
https://ncbi.nlm.nih.gov/pubmed/28243597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/3262495
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