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Establishing elements of a synthetic biology platform for Vaccinia virus production: BioBrick™ design, serum-free virus production and microcarrier-based cultivation of CV-1 cells

Vaccinia virus (VACV) is an established vector for vaccination and is beginning to prove effective as an oncolytic agent. Industrial production of VACV stands to benefit in future from advances made by synthetic biology in genome engineering and standardisation. The CV-1 cell line can be used for VA...

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Bibliografische gegevens
Gepubliceerd in:Heliyon
Hoofdauteurs: Liu, Shuchang, Ruban, Ludmila, Wang, Yaohe, Zhou, Yuhong, Nesbeth, Darren N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294666/
https://ncbi.nlm.nih.gov/pubmed/28203643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2017.e00238
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