Sequestration of Ribosome during Protein Aggregate Formation: Contribution of ribosomal RNA

An understanding of the mechanisms underlying protein aggregation and cytotoxicity of the protein aggregates is crucial in the prevention of several diseases in humans. Ribosome, the cellular protein synthesis machine is capable of acting as a protein folding modulator. The peptidyltransferase cente...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Pathak, Bani K., Mondal, Surojit, Banerjee, Senjuti, Ghosh, Amar Nath, Barat, Chandana
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294636/
https://ncbi.nlm.nih.gov/pubmed/28169307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42017
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