Diagnosis of pancreaticobiliary malignancy by detection of minichromosome maintenance protein 5 in biliary brush cytology

BACKGROUND: Biliary brush cytology is the standard method of evaluating biliary strictures, but is insensitive at detecting malignancy. In pancreaticobiliary cancer minichromosome maintenance replication proteins (MCM 2–7) are dysregulated in the biliary epithelium and MCM5 levels are elevated in bi...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Keane, Margaret G, Huggett, Matthew T, Chapman, Michael H, Johnson, Gavin J, Webster, George J, Thorburn, Douglas, Mackay, James, Pereira, Stephen P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294492/
https://ncbi.nlm.nih.gov/pubmed/28081547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.447
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