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A dominant positive and negative selectable gene for use in mammalian cells.

We have constructed three different fusion genes containing the herpes simplex virus thymidine kinase (HSV tk) and the bacterial neomycin phosphotransferase (neo) genes. All three fusion genes utilize the HSV tk promoter but differ at the junction of their components. We have determined if the fusio...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Schwartz, F, Maeda, N, Smithies, O, Hickey, R, Edelmann, W, Skoultchi, A, Kucherlapati, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1991
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52939/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1720540/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.23.10416
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