DNA binding by the archaeal histone HMf results in positive supercoiling.
HMf, a histone from the hyperthermophilic archaeon Methanothermus fervidus binds double-stranded DNA molecules in vitro, forming compact structures that visibly resemble eukaryal nucleosomes. We show here that HMf binding increases the helical periodicity of DNA molecules to approximately 11 base pa...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52935/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1660135/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.23.10397 |
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