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Evidence for disulfide bonds in SR Protein Kinase 1 (SRPK1) that are required for activity and nuclear localization

Serine/arginine protein kinases (SRPKs) phosphorylate Arg/Ser dipeptide-containing proteins that play crucial roles in a broad spectrum of basic cellular processes. The existence of a large internal spacer sequence that separates the bipartite kinase catalytic core is a unique structural feature of...

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發表在:PLoS One
Main Authors: Koutroumani, Maria, Papadopoulos, Georgios E., Vlassi, Metaxia, Nikolakaki, Eleni, Giannakouros, Thomas
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293202/
https://ncbi.nlm.nih.gov/pubmed/28166275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171328
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