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Small RNA-directed epigenetic programming of embryonic stem cell cardiac differentiation

Microinjection of small noncoding RNAs in one-cell embryos was reported in several instances to result in transcriptional activation of target genes. To determine the molecular mechanisms involved and to explore whether such epigenetic regulations could play a role in early development, we used a ce...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Ghanbarian, Hossein, Wagner, Nicole, Michiels, Jean-François, Cuzin, François, Wagner, Kay-Dietrich, Rassoulzadegan, Minoo
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292948/
https://ncbi.nlm.nih.gov/pubmed/28165496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41799
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