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Hyperplexing: A Method for Higher-Order Multiplexed Quantitative Proteomics Provides a Map of the Dynamic Response to Rapamycin in Yeast

Large-scale quantitative proteomics can provide a near-global view of cellular protein abundance. Yet, the time, effort, and expertise required to achieve reasonable protein coverage and reliable quantification have limited the broad application of this technology. To fully leverage mass spectrometr...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Dephoure, Noah, Gygi, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292868/
https://ncbi.nlm.nih.gov/pubmed/22457332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2002548
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