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Novel APC-like properties of human NK cells directly regulate T cell activation

Initiation of the adaptive immune response is dependent on the priming of naive T cells by APCs. Proteomic analysis of unactivated and activated human NK cell membrane–enriched fractions demonstrated that activated NK cells can efficiently stimulate T cells, since they upregulate MHC class II molecu...

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Detalhes bibliográficos
Main Authors: Hanna, Jacob, Gonen-Gross, Tsufit, Fitchett, Jonathan, Rowe, Tony, Daniels, Mark, Arnon, Tal I., Gazit, Roi, Joseph, Aviva, Schjetne, Karoline W., Steinle, Alexander, Porgador, Angel, Mevorach, Dror, Goldman-Wohl, Debra, Yagel, Simcha, LaBarre, Michael J., Buckner, Jane H., Mandelboim, Ofer
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC529284/
https://ncbi.nlm.nih.gov/pubmed/15578093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200422787
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