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The crucial role of Campylobacter jejuni genes in anti-ganglioside antibody induction in Guillain-Barré syndrome

Molecular mimicry of Campylobacter jejuni lipo-oligosaccharides (LOS) with gangliosides in nervous tissue is considered to induce cross-reactive antibodies that lead to Guillain-Barré syndrome (GBS), an acute polyneuropathy. To determine whether specific bacterial genes are crucial for the biosynthe...

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Autores principales: Godschalk, Peggy C.R., Heikema, Astrid P., Gilbert, Michel, Komagamine, Tomoko, Ang, C. Wim, Glerum, Jobine, Brochu, Denis, Li, Jianjun, Yuki, Nobuhiro, Jacobs, Bart C., van Belkum, Alex, Endtz, Hubert P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC529276/
https://ncbi.nlm.nih.gov/pubmed/15578098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200415707
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