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Expression of human endogenous retrovirus-K is strongly associated with the basal-like breast cancer phenotype

Human endogenous retroviruses (HERVs), which make up approximately 8% of the human genome, are overexpressed in some breast cancer cells and tissues but without regard to cancer subtype. We, therefore, analyzed TCGA RNA-Seq data to evaluate differences in expression of the HERV-K family in breast ca...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Johanning, Gary L., Malouf, Gabriel G., Zheng, Xiaofeng, Esteva, Francisco J., Weinstein, John N., Wang-Johanning, Feng, Su, Xiaoping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292751/
https://ncbi.nlm.nih.gov/pubmed/28165048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41960
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