Novel Treatment of Chronic Graft-Versus-Host Disease in Mice Using the ER Stress Reducer 4-Phenylbutyric Acid

Chronic graft-versus-host disease (cGVHD) is a notorious complication of allogeneic hematopoietic stem cell transplantation and causes disabling systemic inflammation and fibrosis. In this novel study, we focused on a relationship between endoplasmic reticulum (ER) stress and cGVHD, and aimed to cre...

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Udgivet i:Sci Rep
Main Authors: Mukai, Shin, Ogawa, Yoko, Urano, Fumihiko, Kudo-Saito, Chie, Kawakami, Yutaka, Tsubota, Kazuo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292729/
https://ncbi.nlm.nih.gov/pubmed/28165054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41939
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