Citrullination of histone H3 drives IL-6 production by bone marrow mesenchymal stem cells in MGUS and multiple myeloma

Multiple myeloma (MM), an incurable plasma cell malignancy, requires localisation within the bone marrow. This microenvironment facilitates crucial interactions between the cancer cells and stromal cell types that permit the tumour to survive and proliferate. There is increasing evidence that the bo...

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Bibliographic Details
Published in:Leukemia
Main Authors: McNee, G, Eales, K L, Wei, W, Williams, D S, Barkhuizen, A, Bartlett, D B, Essex, S, Anandram, S, Filer, A, Moss, P A H, Pratt, G, Basu, S, Davies, C C, Tennant, D A
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292682/
https://ncbi.nlm.nih.gov/pubmed/27400413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.187
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