Adaptations in Basal and Hypothalamic–Pituitary–Adrenal-Activated Deoxycorticosterone Responses Following Ethanol Self-administration in Cynomolgus Monkeys

Acute ethanol activates the hypothalamic–pituitary–adrenal (HPA) axis, while long-term exposure results in a blunted neuroendocrine state, particularly with regards to the primary endpoint, cortisol, the primary glucocorticoid produced in the adrenal cortex. However, it is unknown if this dampened n...

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Bibliographische Detailangaben
Veröffentlicht in:Front Endocrinol (Lausanne)
Hauptverfasser: Jimenez, Vanessa A., Porcu, Patrizia, Morrow, A. Leslie, Grant, Kathleen A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Endocrinology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292619/
https://ncbi.nlm.nih.gov/pubmed/28220108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2017.00019
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