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Psychotropic drugs and liver disease: A critical review of pharmacokinetics and liver toxicity

The liver is the organ by which the majority of substances are metabolized, including psychotropic drugs. There are several pharmacokinetic changes in end-stage liver disease that can interfere with the metabolization of psychotropic drugs. This fact is particularly true in drugs with extensive firs...

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Publicat a:World J Gastrointest Pharmacol Ther
Autors principals: Telles-Correia, Diogo, Barbosa, António, Cortez-Pinto, Helena, Campos, Carlos, Rocha, Nuno B F, Machado, Sérgio
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Inc 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292604/
https://ncbi.nlm.nih.gov/pubmed/28217372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4292/wjgpt.v8.i1.26
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