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Delineation of a previously unrecognized cis-acting element required for HLA class II gene expression.

The cis-acting DNA sequences that control expression of the HLA-DPA and HLA-DQB promoters have been investigated in detail. A set of recombinant plasmids containing 5' promoter deletions as well as site-directed mutants of the DPA and DQB genes were fused to a reporter gene and transfected into huma...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Sugawara, M, Ponath, P D, Shin, J, Yang, Z, Strominger, J L
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52925/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1946454/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.22.10347
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