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Safety and efficacy of patient specific intramuscular injection of HGF plasmid gene therapy on limb perfusion and wound healing in patients with ischemic lower extremity ulceration: Results of the HGF-0205 trial

OBJECTIVES: We have previously reported the results of a dose-finding phase II trial showing that HGF angiogenic gene therapy can increase TcPO2 compared with placebo in patients with critical limb ischemia (CLI). The purpose of this randomized placebo controlled multi-center trial was to further as...

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Detalhes bibliográficos
Publicado no:J Vasc Surg
Main Authors: Powell, Richard J., Goodney, Phillip, Mendelsohn, Farrell O., Moen, Elaine K., Annex, Brian H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292269/
https://ncbi.nlm.nih.gov/pubmed/21146749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2010.07.044
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