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Pharmacokinetics and Pharmacodynamics of Intravenous Levofloxacin at 750 Milligrams and Various Doses of Metronidazole in Healthy Adult Subjects

The purpose of this investigation was to evaluate the steady-state pharmacokinetics, pharmacodynamics, and safety of intravenous levofloxacin at 750 mg administered once daily combined with three different dosages of intravenous metronidazole (500 mg every 8 h [q8h], 1,000 mg q24h, and 1,500 mg q24h...

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Publicado no:Antimicrob Agents Chemother
Principais autores: Sprandel, Kelly A., Schriever, Christopher A., Pendland, Susan L., Quinn, John P., Gotfried, Mark H., Hackett, Suzanne, Graham, Mary Beth, Danziger, Larry H., Rodvold, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2004
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC529226/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15561831/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.12.4597-4605.2004
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