β-Lactamase Gene Expression in a Penicillin-Resistant Bacillus anthracis Strain

Expression of the bla1 and bla2 genes in an archetypal Bacillus anthracis strain is insufficient for penicillin resistance. In a penicillin-resistant clinical isolate, both genes are highly transcribed, but bla1 is the major contributor to high-level resistance to ampicillin. Differential expression...

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Bibliographic Details
Main Authors: Chen, Yahua, Tenover, Fred C., Koehler, Theresa M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC529205/
https://ncbi.nlm.nih.gov/pubmed/15561870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.12.4873-4877.2004
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