α2AP regulates vascular alteration by inhibiting VEGF signaling in systemic sclerosis: the roles of α2AP in vascular dysfunction in systemic sclerosis

BACKGROUND: Systemic sclerosis (SSc) is a connective tissues disease of unknown origin characterized by vascular damage and extensive fibrosis. Recently, we demonstrated that α2-antiplasmin (α2AP) is associated with the development of fibrosis in SSc. We herein investigate the roles of α2AP in vascu...

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Vydáno v:Arthritis Res Ther
Hlavní autoři: Kanno, Yosuke, Shu, En, Kanoh, Hiroyuki, Matsuda, Ayaka, Seishima, Mariko
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291960/
https://ncbi.nlm.nih.gov/pubmed/28159016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1227-y
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