Clinically Relevant Interpretation of Genotype and Relationship to Plasma Drug Concentrations for Resistance to Saquinavir-Ritonavir in Human Immunodeficiency Virus Type 1 Protease Inhibitor-Experienced Patients

It has been shown that virological protease inhibitor (PI) resistance mutations present at the initiation of saquinavir (SQV) plus ritonavir (RTV) therapy in PI-experienced patients are the strongest predictors of virological response. But most of the current resistance algorithms are adapted for un...

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Main Authors: Marcelin, Anne-Geneviève, Dalban, Cécile, Peytavin, Gilles, Lamotte, Claire, Agher, Rachid, Delaugerre, Constance, Wirden, Marc, Conan, Françoise, Dantin, Sylvie, Katlama, Christine, Costagliola, Dominique, Calvez, Vincent
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC529185/
https://ncbi.nlm.nih.gov/pubmed/15561845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.12.4687-4692.2004
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