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Sustained morphine administration induces TRPM8 dependent cold hyperalgesia

It is not uncommon for patients chronically treated with opioids to exhibit opioid induced hyperalgesia (OIH), and this has been widely reported both clinically and experimentally. The molecular substrate for this hyperalgesia is multifaceted, and associated with a complex neural reorganization even...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Pain
Hauptverfasser: Gong, Kerui, Jasmin, Luc
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291755/
https://ncbi.nlm.nih.gov/pubmed/27845197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2016.10.015
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