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Protein kinases: mechanisms and downstream targets in inflammation mediated obesity and insulin resistance
Obesity induced low-grade inflammation (metaflammation) impairs insulin receptor signaling (IRS). This has been implicated in the development of insulin resistance. Insulin signaling in the target tissues is mediated by stress kinases such as p38 mitogen-activated protein kinase (MAPK), c-Jun NH2-te...
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| Gepubliceerd in: | Mol Cell Biochem |
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| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5291752/ https://ncbi.nlm.nih.gov/pubmed/27868170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-016-2878-8 |
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