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Mitochondrial quality-control dysregulation in conditional HO-1(–/–) mice
The heme oxygenase-1 (Hmox1; HO-1) pathway was tested for defense of mitochondrial quality control in cardiomyocyte-specific Hmox1 KO mice (HO-1[CM](–/–)) exposed to oxidative stress (100% O(2)). After 48 hours of exposure, these mice showed persistent cardiac inflammation and oxidative tissue damag...
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Argitaratua izan da: | JCI Insight |
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Egile Nagusiak: | , , |
Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
American Society for Clinical Investigation
2017
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5291731/ https://ncbi.nlm.nih.gov/pubmed/28194437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89676 |
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