Deletion of neuropilin 2 enhances detrusor contractility following bladder outlet obstruction

Chronic urethral obstruction and the ensuing bladder wall remodeling can lead to diminished bladder smooth muscle (BSM) contractility and debilitating lower urinary tract symptoms. No effective pharmacotherapy exists to restore BSM contractile function. Neuropilin 2 (Nrp2) is a transmembrane protein...

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Pubblicato in:JCI Insight
Autori principali: Vasquez, Evalynn, Cristofaro, Vivian, Lukianov, Stefan, Burkhard, Fiona C., Gheinani, Ali Hashemi, Monastyrskaya, Katia, Bielenberg, Diane R., Sullivan, Maryrose P., Adam, Rosalyn M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291730/
https://ncbi.nlm.nih.gov/pubmed/28194441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90617
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