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Deletion of neuropilin 2 enhances detrusor contractility following bladder outlet obstruction

Chronic urethral obstruction and the ensuing bladder wall remodeling can lead to diminished bladder smooth muscle (BSM) contractility and debilitating lower urinary tract symptoms. No effective pharmacotherapy exists to restore BSM contractile function. Neuropilin 2 (Nrp2) is a transmembrane protein...

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Publicado en:JCI Insight
Main Authors: Vasquez, Evalynn, Cristofaro, Vivian, Lukianov, Stefan, Burkhard, Fiona C., Gheinani, Ali Hashemi, Monastyrskaya, Katia, Bielenberg, Diane R., Sullivan, Maryrose P., Adam, Rosalyn M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291730/
https://ncbi.nlm.nih.gov/pubmed/28194441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90617
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