Deletion of neuropilin 2 enhances detrusor contractility following bladder outlet obstruction

Chronic urethral obstruction and the ensuing bladder wall remodeling can lead to diminished bladder smooth muscle (BSM) contractility and debilitating lower urinary tract symptoms. No effective pharmacotherapy exists to restore BSM contractile function. Neuropilin 2 (Nrp2) is a transmembrane protein...

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Enregistré dans:
Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Vasquez, Evalynn, Cristofaro, Vivian, Lukianov, Stefan, Burkhard, Fiona C., Gheinani, Ali Hashemi, Monastyrskaya, Katia, Bielenberg, Diane R., Sullivan, Maryrose P., Adam, Rosalyn M.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291730/
https://ncbi.nlm.nih.gov/pubmed/28194441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90617
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