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The structurally disordered paramyxovirus nucleocapsid protein tail domain is a regulator of the mRNA transcription gradient

The paramyxovirus RNA-dependent RNA-polymerase (RdRp) complex loads onto the nucleocapsid protein (N)–encapsidated viral N:RNA genome for RNA synthesis. Binding of the RdRp of measles virus (MeV), a paramyxovirus archetype, is mediated through interaction with a molecular recognition element (MoRE)...

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發表在:Sci Adv
Main Authors: Cox, Robert M., Krumm, Stefanie A., Thakkar, Vidhi D., Sohn, Maximilian, Plemper, Richard K.
格式: Artigo
語言:Inglês
出版: American Association for the Advancement of Science 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291697/
https://ncbi.nlm.nih.gov/pubmed/28168220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1602350
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