Silymarin suppresses basal and stimulus-induced activation, exhaustion, differentiation, and inflammatory markers in primary human immune cells

Silymarin (SM), and its flavonolignan components, alter cellular metabolism and inhibit inflammatory status in human liver and T cell lines. In this study, we hypothesized that SM suppresses both acute and chronic immune activation (CIA), including in the context of HIV infection. SM treatment suppr...

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Publicado en:PLoS One
Autores principales: Lovelace, Erica S., Maurice, Nicholas J., Miller, Hannah W., Slichter, Chloe K., Harrington, Robert, Magaret, Amalia, Prlic, Martin, De Rosa, Stephen, Polyak, Stephen J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291532/
https://ncbi.nlm.nih.gov/pubmed/28158203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171139
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