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Recursive random forest algorithm for constructing multilayered hierarchical gene regulatory networks that govern biological pathways

BACKGROUND: Present knowledge indicates a multilayered hierarchical gene regulatory network (ML-hGRN) often operates above a biological pathway. Although the ML-hGRN is very important for understanding how a pathway is regulated, there is almost no computational algorithm for directly constructing M...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Deng, Wenping, Zhang, Kui, Busov, Victor, Wei, Hairong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291523/
https://ncbi.nlm.nih.gov/pubmed/28158291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171532
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