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Power Calculations to Select Instruments for Clinical Trial Secondary Endpoints. A Case Study of Instrument Selection for Post-Traumatic Stress Symptoms in Subjects with Acute Respiratory Distress Syndrome

Rationale: After the sample size of a randomized clinical trial (RCT) is set by the power requirement of its primary endpoint, investigators select secondary endpoints while unable to further adjust sample size. How the sensitivity and specificity of an instrument used to measure these outcomes, tog...

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Bibliographische Detailangaben
Veröffentlicht in:Ann Am Thorac Soc
Hauptverfasser: Sjoding, Michael W., Schoenfeld, David A., Brown, Samuel M., Hough, Catherine L., Yealy, Donald M., Moss, Marc, Angus, Derek C., Iwashyna, Theodore J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291478/
https://ncbi.nlm.nih.gov/pubmed/27788018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201608-585OC
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