A combined approach of hollow microneedles and nanocarriers for skin immunization with plasmid DNA encoding ovalbumin

The aim of this study was to investigate the use of different types of microneedles (MNs) and nanocarriers for in vitro skin permeation and in vivo immunization of plasmid DNA encoding ovalbumin (pOVA). In vitro skin permeation studies indicated that hollow MNs had a superior enhancing effect on ski...

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Библиографические подробности
Опубликовано в: :Int J Nanomedicine
Главные авторы: Pamornpathomkul, Boonnada, Wongkajornsilp, Adisak, Laiwattanapaisal, Wanida, Rojanarata, Theerasak, Opanasopit, Praneet, Ngawhirunpat, Tanasait
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2017
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291464/
https://ncbi.nlm.nih.gov/pubmed/28184159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S125945
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