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Loss of the mitochondrial protein-only ribonuclease P complex causes aberrant tRNA processing and lethality in Drosophila

Proteins encoded by mitochondrial DNA are translated using mitochondrially encoded tRNAs and rRNAs. As with nuclear encoded tRNAs, mitochondrial tRNAs must be processed to become fully functional. The mitochondrial form of ribonuclease P (mt:RNase P) is responsible for 5′-end maturation and is compr...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Sen, Aditya, Karasik, Agnes, Shanmuganathan, Aranganathan, Mirkovic, Elena, Koutmos, Markos, Cox, Rachel T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291253/
https://ncbi.nlm.nih.gov/pubmed/27131785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw338
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