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Loss of the mitochondrial protein-only ribonuclease P complex causes aberrant tRNA processing and lethality in Drosophila

Proteins encoded by mitochondrial DNA are translated using mitochondrially encoded tRNAs and rRNAs. As with nuclear encoded tRNAs, mitochondrial tRNAs must be processed to become fully functional. The mitochondrial form of ribonuclease P (mt:RNase P) is responsible for 5′-end maturation and is compr...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Sen, Aditya, Karasik, Agnes, Shanmuganathan, Aranganathan, Mirkovic, Elena, Koutmos, Markos, Cox, Rachel T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
Onderwerpen:
RNA
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291253/
https://ncbi.nlm.nih.gov/pubmed/27131785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw338
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