Regulation of DNA Translocation Efficiency Within the Chromatin Remodeler RSC/Sth1 Potentiates Nucleosome Sliding and Ejection

The RSC chromatin remodeler slides and ejects nucleosomes, utilizing a catalytic subunit (Sth1) with DNA translocation activity, which can pump DNA around the nucleosome. A central question is whether and how DNA translocation is regulated to achieve sliding versus ejection. Here, we report the regu...

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Bibliographic Details
Published in:Mol Cell
Main Authors: Clapier, Cedric R., Kasten, Margaret M., Parnell, Timothy J., Viswanathan, Ramya, Szerlong, Heather, Sirinakis, George, Zhang, Yongli, Cairns, Bradley R.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291166/
https://ncbi.nlm.nih.gov/pubmed/27153540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.03.032
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