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Longitudinal in vivo bioimaging of hepatocyte transcription factor activity following cholestatic liver injury in mice

Molecular mechanisms regulating liver repair following cholestatic injury remain largely unknown. We have combined a mouse model of acute cholestatic liver injury, partial bile duct ligation (pBDL), with a novel longitudinal bioimaging methodology to quantify transcription factor activity during hep...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Delhove, Juliette M. K. M., Buckley, Suzanne M. K., Perocheau, Dany P., Karda, Rajvinder, Arbuthnot, Patrick, Henderson, Neil C., Waddington, Simon N., McKay, Tristan R.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291111/
https://ncbi.nlm.nih.gov/pubmed/28157201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41874
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