α Actinin 4 (ACTN4) Regulates Glucocorticoid Receptor-mediated Transactivation and Transrepression in Podocytes

Glucocorticoids are a general class of steroids that possess renoprotective activity in glomeruli through their interaction with the glucocorticoid receptor. However, the mechanisms by which glucocorticoids ameliorate proteinuria and glomerular disease are not well understood. In this study, we demo...

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Vydáno v:J Biol Chem
Hlavní autoři: Zhao, Xuan, Khurana, Simran, Charkraborty, Sharmistha, Tian, Yuqian, Sedor, John R., Bruggman, Leslie A., Kao, Hung-Ying
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290941/
https://ncbi.nlm.nih.gov/pubmed/27998979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.755546
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