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Inhibition of cyst growth in PCK and Wpk rat models of polycystic kidney disease with low doses of peroxisome proliferator-activated receptor γ agonists

BACKGROUND AND OBJECTIVES: The studies were designed to test the efficacy of two peroxisome proliferator-activated receptor γ (PPARγ) agonists in two rodent models of polycystic kidney disease (PKD). MATERIALS AND METHODS: The PCK rat is a slowly progressing cystic model while the Wpk(-/-) rat is a...

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Publicat a:J Transl Int Med
Autors principals: Flaig, Stephanie M., Gattone, Vincent H., Blazer-Yost, Bonnie L.
Format: Artigo
Idioma:Inglês
Publicat: De Gruyter 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290882/
https://ncbi.nlm.nih.gov/pubmed/28191533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/jtim-2016-0028
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