Kinetic Analysis of the Oxidative Conversion of the [4Fe-4S](2+) Cluster of FNR to a [2Fe-2S](2+) Cluster

The ability of FNR to sense and respond to cellular O(2) levels depends on its [4Fe-4S](2+) cluster. In the presence of O(2), the [4Fe-4S](2+) cluster is converted to a [2Fe-2S](2+) cluster, which inactivates FNR as a transcriptional regulator. In this study, we demonstrate that ∼2 Fe(2+) ions are r...

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Veröffentlicht in:J Bacteriol
Hauptverfasser: Sutton, Victoria R., Mettert, Erin L., Beinert, Helmut, Kiley, Patricia J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2004
Schlagworte:
Enzymes and Proteins
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC529072/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15547274/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.186.23.8018-8025.2004
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