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Genetic Characterization of the Bile Salt Response in Lactobacillus plantarum and Analysis of Responsive Promoters In Vitro and In Situ in the Gastrointestinal Tract

In this paper we describe the growth, morphological, and genetic responses of Lactobacillus plantarum WCFS1 to bile. Growth experiments revealed that a stepwise increase in the porcine bile concentration led to a gradual decrease in the maximal growth rate. Moreover, the final density reached by an...

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Autors principals: Bron, Peter A., Marco, Maria, Hoffer, Sally M., Van Mullekom, Esther, de Vos, Willem M., Kleerebezem, Michiel
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC529069/
https://ncbi.nlm.nih.gov/pubmed/15547253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.23.7829-7835.2004
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