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Thrombospondin-1 mediates multi-walled carbon nanotube induced impairment of arteriolar dilation

Pulmonary exposure to multi-walled carbon nanotubes (MWCNT) has been shown to disrupt endothelium-dependent arteriolar dilation in the peripheral microcirculation. The molecular mechanisms behind these arteriolar disruptions have yet to be fully elucidated. The secreted matricellular matrix protein...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nanotoxicology
Hauptverfasser: Mandler, W. Kyle, Nurkiewicz, Timothy R., Porter, Dale W., Olfert, I. Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290593/
https://ncbi.nlm.nih.gov/pubmed/28024456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17435390.2016.1277275
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