Signatures of malaria-associated pathology revealed by high-resolution whole-blood transcriptomics in a rodent model of malaria

The influence of parasite genetic factors on immune responses and development of severe pathology of malaria is largely unknown. In this study, we performed genome-wide transcriptomic profiling of mouse whole blood during blood-stage infections of two strains of the rodent malaria parasite Plasmodiu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lin, Jing-wen, Sodenkamp, Jan, Cunningham, Deirdre, Deroost, Katrien, Tshitenge, Tshibuayi Christine, McLaughlin, Sarah, Lamb, Tracey J., Spencer-Dene, Bradley, Hosking, Caroline, Ramesar, Jai, Janse, Chris J., Graham, Christine, O’Garra, Anne, Langhorne, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290525/
https://ncbi.nlm.nih.gov/pubmed/28155887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41722
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