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3′-End Polishing of the Kinetoplastid Spliced Leader RNA Is Performed by SNIP, a 3′→5′ Exonuclease with a Motley Assortment of Small RNA Substrates

In all trypanosomatids, trans splicing of the spliced leader (SL) RNA is a required step in the maturation of all nucleus-derived mRNAs. The SL RNA is transcribed with an oligo-U 3′ extension that is removed prior to trans splicing. Here we report the identification and characterization of a nonexos...

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Bibliografiske detaljer
Main Authors: Zeiner, Gusti M., Hitchcock, Robert A., Sturm, Nancy R., Campbell, David A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC529039/
https://ncbi.nlm.nih.gov/pubmed/15542846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.23.10390-10396.2004
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